Application
Western blot analysis of SPN Antibody (Center) in HL-60 cell line lysates (35ug/lane). SPN (arrow) was detected using the purified Pab.| Product Name | SPN Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SPN; CD43; Leukosialin; Galactoglycoprotein; Leukocyte sialoglycoprotein; Sialophorin; CD_antigen=CD43; Flags: Precursor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CD43 |
|---|---|
| Alternative Names | SPN CD43 Leukosialin Galactoglycoprotein Leukocyte sialoglycoprotein Sialophorin CD_antigen=CD43 Flags: Precursor |
| Molecular Weight(MW) | 40322 Da |
| Function | One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity) |
| Tissue Specificity | Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 6693 |
|---|
Application
Western blot analysis of SPN Antibody (Center) in HL-60 cell line lysates (35ug/lane). SPN (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
