Application
SPOP Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the SPOP antibody detected the SPOP protein (arrow).| Product Name | SPOP Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SPOP; Speckle-type POZ protein; HIB homolog 1; Roadkill homolog 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SPOP Speckle-type POZ protein HIB homolog 1 Roadkill homolog 1 |
|---|---|
| Molecular Weight(MW) | 42132 Da |
| Function | Inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex (By similarity). In complex with CUL3, involved in ubiquitination of BMI1, H2AFY and DAXX, and probably also in ubiquitination and proteasomal degradation of Gli2 or Gli3 |
| Tissue Specificity | Widely expressed. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 8405 |
|---|---|
| Nucleotide Accession | NP_003554.1 |
Application
SPOP Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the SPOP antibody detected the SPOP protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
