Application
SRA1 Antibody (C-term) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the SRA1 antibody detected the SRA1 protein (arrow).| Product Name | SRA1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SRA1; Steroid receptor RNA activator 1; Steroid receptor RNA activator protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SRA1 Steroid receptor RNA activator 1 Steroid receptor RNA activator protein |
|---|---|
| Molecular Weight(MW) | 25673 Da |
| Function | Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand- dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis |
| Tissue Specificity | Highly expressed in liver and skeletal muscle and to a lesser extent in brain. Also expressed in both normal and tumorigenic breast epithelial cell lines. Significantly up- regulated in human tumors of the breast, ovary, and uterus |
| Cellular Localization | Nucleus. Cytoplasm. |
| Entrez Gene | 10011 |
|---|---|
| Nucleotide Accession | NP_001030312.2 |
Application
SRA1 Antibody (C-term) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the SRA1 antibody detected the SRA1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
