Application
STAMBP Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the STAMBP antibody detected the STAMBP protein (arrow).Application
STAMBP Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the STAMBP antibody detected the STAMBP protein (arrow).Application
STAMBP Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STAMBP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | STAMBP Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | STAMBP; AMSH; STAM-binding protein; Associated molecule with the SH3 domain of STAM; Endosome-associated ubiquitin isopeptidase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | AMSH |
|---|---|
| Alternative Names | STAMBP AMSH STAM-binding protein Associated molecule with the SH3 domain of STAM Endosome-associated ubiquitin isopeptidase |
| Molecular Weight(MW) | 48077 Da |
| Function | Zinc metalloprotease that specifically cleaves 'Lys-63'- linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Functions at the endosome and is able to oppose the ubiquitin-dependent sorting of receptors to lysosomes. Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7 |
| Tissue Specificity | Ubiquitously expressed. |
| Cellular Localization | Nucleus. Membrane; Peripheral membrane protein. Cytoplasm. Early endosome |
| Entrez Gene | 10617 |
|---|---|
| Nucleotide Accession | NP_964010.1 NP_006454.1 |
Application
STAMBP Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the STAMBP antibody detected the STAMBP protein (arrow).
Application
STAMBP Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the STAMBP antibody detected the STAMBP protein (arrow).
Application
STAMBP Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STAMBP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
