Application
A.Western blot analysis on HeLa cell lysates using anti-Phospho-Stathmin (pS62) RabMAb (Cat. #AJ1743d), 1:10,000 dilution. Cells were either (A) untreated (B) treated with Calyculin A.Application
B. Immunohistochemical analysis of paraffin-embedded human brain tissue using Phospho-specific anti-Stathmin RabMAb (Cat. #AJ1743d).| Product Name | Stathmin Antibody Phospho (pS62) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | STMN1, LAP18, OP18, Stathmin, pp17;Prosolin;Metablastin;Protein Pr22 |
| Modification | p-S62 |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR1574 |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:2500~10000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C1orf215 LAP18 OP18 |
|---|---|
| Alternative Names | STMN1 LAP18 OP18 Stathmin pp17 Prosolin Metablastin Protein Pr22 |
| Molecular Weight(MW) | 17303 Da |
| Function | Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser- 16 may be required for axon formation during neurogenesis Involved in the control of the learned and innate fear (By similarity) |
| Tissue Specificity | Ubiquitous. Expression is strongest in fetal and adult brain, spinal cord, and cerebellum, followed by thymus, bone marrow, testis, and fetal liver. Expression is intermediate in colon, ovary, placenta, uterus, and trachea, and is readily detected at substantially lower levels in all other tissues examined. Lowest expression is found in adult liver. Present in much greater abundance in cells from patients with acute leukemia of different subtypes than in normal peripheral blood lymphocytes, non-leukemic proliferating lymphoid cells, bone marrow cells, or cells from patients with chronic lymphoid or myeloid leukemia |
| Cellular Localization | Cytoplasm, cytoskeleton. |
| Entrez Gene | 3925 |
|---|
Application
A.Western blot analysis on HeLa cell lysates using anti-Phospho-Stathmin (pS62) RabMAb (Cat. #AJ1743d), 1:10,000 dilution. Cells were either (A) untreated (B) treated with Calyculin A.
Application
B. Immunohistochemical analysis of paraffin-embedded human brain tissue using Phospho-specific anti-Stathmin RabMAb (Cat. #AJ1743d).| Application Notes | WB:1:2500~10000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
