Application
STMN1 Antibody (Center) western blot analysis in K562,Jurkat,HL-60,MDA-MB435,MDA-MB231 cell line lysates (35ug/lane).This demonstrates the STMN1 antibody detected the STMN1 protein (arrow).Application
STMN1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the STMN1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.Application
STMN1 Antibody (Center) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | STMN1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | STMN1; C1orf215; LAP18; OP18; Stathmin; Leukemia-associated phosphoprotein p18; Metablastin; Oncoprotein 18; Phosphoprotein p19; Prosolin; Protein Pr22; pp17 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C1orf215 LAP18 OP18 |
|---|---|
| Alternative Names | STMN1 C1orf215 LAP18 OP18 Stathmin Leukemia-associated phosphoprotein p18 Metablastin Oncoprotein 18 Phosphoprotein p19 Prosolin Protein Pr22 pp17 |
| Molecular Weight(MW) | 17303 Da |
| Function | Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser- 16 may be required for axon formation during neurogenesis Involved in the control of the learned and innate fear (By similarity) |
| Tissue Specificity | Ubiquitous. Expression is strongest in fetal and adult brain, spinal cord, and cerebellum, followed by thymus, bone marrow, testis, and fetal liver. Expression is intermediate in colon, ovary, placenta, uterus, and trachea, and is readily detected at substantially lower levels in all other tissues examined. Lowest expression is found in adult liver. Present in much greater abundance in cells from patients with acute leukemia of different subtypes than in normal peripheral blood lymphocytes, non-leukemic proliferating lymphoid cells, bone marrow cells, or cells from patients with chronic lymphoid or myeloid leukemia |
| Cellular Localization | Cytoplasm, cytoskeleton. |
| Entrez Gene | 3925 |
|---|
Application
STMN1 Antibody (Center) western blot analysis in K562,Jurkat,HL-60,MDA-MB435,MDA-MB231 cell line lysates (35ug/lane).This demonstrates the STMN1 antibody detected the STMN1 protein (arrow).
Application
STMN1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the STMN1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
STMN1 Antibody (Center) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
