Application
Western blot analysis of hSTEP-Q155 in mouse brain tissue lysates (35ug/lane). STEP (arrow) was detected using the purified PabApplication
Western blot analysis of hSTEP-Q155 in HepG2 cell line lysates (35ug/lane). STEP (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with STEP antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | STEP / PTPN5 Antibody (N-Term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PTPN5; Tyrosine-protein phosphatase non-receptor type 5; Neural-specific protein-tyrosine phosphatase; Striatum-enriched protein-tyrosine phosphatase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PTPN5 Tyrosine-protein phosphatase non-receptor type 5 Neural-specific protein-tyrosine phosphatase Striatum-enriched protein-tyrosine phosphatase |
|---|---|
| Molecular Weight(MW) | 63538 Da |
| Function | May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors |
| Tissue Specificity | This STEP / PTPN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148~177 amino acids from the N-terminal region of human STEP. |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity) |
| Entrez Gene | 84867 |
|---|
Application
Western blot analysis of hSTEP-Q155 in mouse brain tissue lysates (35ug/lane). STEP (arrow) was detected using the purified Pab
Application
Western blot analysis of hSTEP-Q155 in HepG2 cell line lysates (35ug/lane). STEP (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with STEP antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
