Application
STXBP5 Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the STXBP5 antibody detected the STXBP5 protein (arrow).| Product Name | STXBP5 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | STXBP5; LLGL3; Syntaxin-binding protein 5; Lethal(2) giant larvae protein homolog 3; Tomosyn-1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | LLGL3 |
|---|---|
| Alternative Names | STXBP5 LLGL3 Syntaxin-binding protein 5 Lethal(2) giant larvae protein homolog 3 Tomosyn-1 |
| Molecular Weight(MW) | 127573 Da |
| Function | Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Competes with STXBP1 for STX1 binding (By similarity) |
| Tissue Specificity | This STXBP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 462-492 amino acids from the Central region of human STXBP5. |
| Cellular Localization | Cytoplasm (By similarity). Cell membrane; Peripheral membrane protein (By similarity). Cytoplasmic vesicle membrane; Peripheral membrane protein (By similarity). Cytoplasmic vesicle, secretory vesicle, synaptic vesicle (By similarity). Cell junction, synapse (By similarity). Note=Cytoplasmic, and associated with vesicular membranes and the plasma membrane Detected at synapses and on synaptic vesicles (By similarity) |
| Entrez Gene | 134957 |
|---|---|
| Nucleotide Accession | NP_640337.3 NP_001121187.1 |
Application
STXBP5 Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the STXBP5 antibody detected the STXBP5 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
