Application
STXBP1 Antibody (N-term) western blot analysis in mouse cerebellum tissue and Jurkat cell line lysates (35ug/lane).This demonstrates the STXBP1 antibody detected the STXBP1 protein (arrow).Application
STXBP1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the STXBP1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
STXBP1 Antibody (N-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | STXBP1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | STXBP1; UNC18A; Syntaxin-binding protein 1; MUNC18-1; N-Sec1; Protein unc-18 homolog 1; Protein unc-18 homolog A; p67 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | UNC18A |
|---|---|
| Alternative Names | STXBP1 UNC18A Syntaxin-binding protein 1 MUNC18-1 N-Sec1 Protein unc-18 homolog 1 Protein unc-18 homolog A p67 |
| Molecular Weight(MW) | 67569 Da |
| Function | May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions |
| Tissue Specificity | Brain and spinal cord. Highly enriched in axons |
| Cellular Localization | Cytoplasm. Membrane; Peripheral membrane protein |
| Entrez Gene | 6812 |
|---|
Application
STXBP1 Antibody (N-term) western blot analysis in mouse cerebellum tissue and Jurkat cell line lysates (35ug/lane).This demonstrates the STXBP1 antibody detected the STXBP1 protein (arrow).
Application
STXBP1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the STXBP1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
STXBP1 Antibody (N-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
