Application
Western blot analysis of SULT2B1a/b antibody (N-term) (Cat.# Ap2604a) in HL60 cell line lysates (35ug/lane). SULT2B1a/b (arrow) was detected using the purified Pab.| Product Name | SULT2B1a/b Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SULT2B1; HSST2; Sulfotransferase family cytosolic 2B member 1; Alcohol sulfotransferase; Hydroxysteroid sulfotransferase 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HSST2 |
|---|---|
| Alternative Names | SULT2B1 HSST2 Sulfotransferase family cytosolic 2B member 1 Alcohol sulfotransferase Hydroxysteroid sulfotransferase 2 |
| Molecular Weight(MW) | 41308 Da |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol |
| Tissue Specificity | Expressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung |
| Cellular Localization | Cytoplasm. Microsome. Nucleus. Note=Phosphorylation of Ser-348 is required for translocation to the nucleus |
Application
Western blot analysis of SULT2B1a/b antibody (N-term) (Cat.# Ap2604a) in HL60 cell line lysates (35ug/lane). SULT2B1a/b (arrow) was detected using the purified Pab.| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
