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SUMO4 Antibody (V55 Mutant)

Catalog Number:OM222316
OM222316
Discount Price
OM222316-100ul
1~2 Week
100ul
OM222316-50ul
50ul
OM222316-20ul
20ul
1~2 Week
Product Profile
Product Name SUMO4 Antibody (V55 Mutant)
Antibody Type Primary Antibodies
Antigen Alias SUMO4; SMT3H4; Small ubiquitin-related modifier 4; Small ubiquitin-like protein 4
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms SMT3H4
Alternative Names SUMO4
SMT3H4
Small ubiquitin-related modifier 4
Small ubiquitin-like protein 4
Molecular Weight(MW) 10685 Da
Function Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I
Tissue Specificity Expressed mainly in adult and embryonic kidney. Expressed at various levels in immune tissues, with the highest expression in the lymph node and spleen
Database Links
Entrez Gene 387082
Application

Application

Western blot analysis of SUMO4 Antibody (V55 Mutant) in HepG2 cell line lysate (35ug/lane). SUMO4 mutant (arrow) was detected using the purified Pab (1:80 dilution).

Application

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with SUMO4 antibody (V55 Mutant) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Application

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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