Application
A. Western blot analysis on human skeletal muscle lysate using anti-Synip RabMAb (Cat. #AJ1754a), dilution 1:1,000.Application
B. Immunohistochemical analysis of paraffin-embedded human lung carcinoma using anti-Synip RabMAb (Cat. #AJ1754a).| Product Name | Synip Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP302Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Molecular Weight(MW) | 61662 Da |
|---|---|
| Function | Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity) |
| Tissue Specificity | A synthetic peptide corresponding to residues near the C-terminus of the PDZ domain of human Synip was used as immunogen. This antibody is predicted to detect the isoform 2 base on sequence analysis. |
| Cellular Localization | Cytoplasm (By similarity). |
| Entrez Gene | 252983 |
|---|
Application
A. Western blot analysis on human skeletal muscle lysate using anti-Synip RabMAb (Cat. #AJ1754a), dilution 1:1,000.
Application
B. Immunohistochemical analysis of paraffin-embedded human lung carcinoma using anti-Synip RabMAb (Cat. #AJ1754a).| Application Notes | WB:1:500~1000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
