Application
The anti-Synphilin-1 C-term Pab is used in Western blot to detect Synphilin-1 in mouse brain lysate.| Product Name | Synphilin-1 (SNCAIP) Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SNCAIP; Synphilin-1; Alpha-synuclein-interacting protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SNCAIP Synphilin-1 Alpha-synuclein-interacting protein |
|---|---|
| Molecular Weight(MW) | 100409 Da |
| Function | Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1 |
| Tissue Specificity | Detected in brain (at protein level). Widely expressed, with highest levels in brain, heart and placenta |
| Cellular Localization | Cytoplasm. Note=Detected in cytoplasmic inclusion bodies, together with SNCA |
Application
The anti-Synphilin-1 C-term Pab is used in Western blot to detect Synphilin-1 in mouse brain lysate.| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
