Application
A. Western blot analysis on fetal brain lysate using anti-SynGAP RabMAb (Cat. #AJ1753a), dilution 1:1000.| Product Name | SynGAP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SYNGAP1, KIAA1938, Ras GTPase-activating protein SynGAP, Neuronal RasGAP |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR2883Y |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:1000~5000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1938 |
|---|---|
| Alternative Names | SYNGAP1 KIAA1938 Ras GTPase-activating protein SynGAP Neuronal RasGAP |
| Molecular Weight(MW) | 148284 Da |
| Function | Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR- mediated miniature excitatory postsynaptic currents. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By similarity) |
| Tissue Specificity | A synthetic peptide corresponding to residues on the C-terminus of human SynGAP was used as an immunogen. |
| Entrez Gene | 8831 |
|---|
Application
A. Western blot analysis on fetal brain lysate using anti-SynGAP RabMAb (Cat. #AJ1753a), dilution 1:1000.| Application Notes | WB:1:1000~5000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
