Application
TAF1 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the TAF1 antibody detected the TAF1 protein (arrow).| Product Name | TAF1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TAF1; BA2R; CCG1; CCGS; TAF2A; Transcription initiation factor TFIID subunit 1; Cell cycle gene 1 protein; TBP-associated factor 250 kDa; Transcription initiation factor TFIID 250 kDa subunit |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BA2R CCG1 CCGS TAF2A |
|---|---|
| Alternative Names | TAF1 BA2R CCG1 CCGS TAF2A Transcription initiation factor TFIID subunit 1 Cell cycle gene 1 protein TBP-associated factor 250 kDa Transcription initiation factor TFIID 250 kDa subunit |
| Molecular Weight(MW) | 212677 Da |
| Function | Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53 Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA- binding activity. Essential for progression of the G1 phase of the cell cycle |
| Tissue Specificity | This TAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1860-1893 amino acids from the C-terminal region of human TAF1. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 6872 |
|---|---|
| Nucleotide Accession | NP_620278.1 NP_004597.2 |
Application
TAF1 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the TAF1 antibody detected the TAF1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
