Application
TAS2R43 Antibody (Center) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the TAS2R43 antibody detected the TAS2R43 protein (arrow).| Product Name | TAS2R43 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TAS2R43;Taste receptor type 2 member 43; Taste receptor type 2 member 43; Taste receptor type 2 member 52 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TAS2R43 Taste receptor type 2 member 43 Taste receptor type 2 member 43 Taste receptor type 2 member 52 |
|---|---|
| Molecular Weight(MW) | 35599 Da |
| Function | Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. May act as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways (By similarity) |
| Tissue Specificity | Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells Expressed in airway epithelia |
| Cellular Localization | Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia |
| Entrez Gene | 259289 |
|---|
Application
TAS2R43 Antibody (Center) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the TAS2R43 antibody detected the TAS2R43 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
