Application
TBC1D2 Antibody (Center) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the TBC1D2 antibody detected the TBC1D2 protein (arrow).| Product Name | TBC1D2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TBC1D2; PARIS1; PP8997; TBC1D2A; TBC1 domain family member 2A; Armus; Prostate antigen recognized and identified by SEREX 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PARIS1 PP8997 TBC1D2A |
|---|---|
| Alternative Names | TBC1D2 PARIS1 PP8997 TBC1D2A TBC1 domain family member 2A Armus Prostate antigen recognized and identified by SEREX 1 |
| Molecular Weight(MW) | 105414 Da |
| Function | Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion |
| Tissue Specificity | Expressed in a broad range of tissues, especially in kidney, liver, lung and placenta. Also expressed in keratinocytes and epithelia-containing organs. Isoform 2 is differentially expressed in prostate normal and cancer cells (at protein level) |
| Cellular Localization | Cytoplasm. Cytoplasmic vesicle. Cell junction |
| Entrez Gene | 55357 |
|---|---|
| Nucleotide Accession | NP_060891.3 |
Application
TBC1D2 Antibody (Center) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the TBC1D2 antibody detected the TBC1D2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
