Application
Western blot analysis of anti-TBRG1 Pab in K562 cell line lysates (35ug/lane). TBRG1(arrow) was detected using the purified Pab (1:60 dilution).| Product Name | TBRG1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TBRG1; NIAM; Transforming growth factor beta regulator 1; Nuclear interactor of ARF and Mdm2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NIAM |
|---|---|
| Alternative Names | TBRG1 NIAM Transforming growth factor beta regulator 1 Nuclear interactor of ARF and Mdm2 |
| Molecular Weight(MW) | 44946 Da |
| Function | Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability |
| Tissue Specificity | Widely expressed at low levels in most tissues, with highest levels in pancreas, lung and liver Expression is decreased in primary tumors including lung, liver, breast, pancreas and kidney carcinomas, chronic lymphocytic leukemia and diffuse large B-cell lymphoma |
| Cellular Localization | Nucleus. |
| Entrez Gene | 84897 |
|---|
Application
Western blot analysis of anti-TBRG1 Pab in K562 cell line lysates (35ug/lane). TBRG1(arrow) was detected using the purified Pab (1:60 dilution).| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
