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TBX6 Antibody (Center W158)

Catalog Number:OM222675
OM222675
Discount Price
OM222675-100ul
1~2 Week
100ul
OM222675-50ul
50ul
OM222675-20ul
20ul
1~2 Week
Product Profile
Product Name TBX6 Antibody (Center W158)
Antibody Type Primary Antibodies
Antigen Alias TBX6; T-box transcription factor TBX6
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBFC
WB:1:50~100 FC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names TBX6
T-box transcription factor TBX6
Molecular Weight(MW) 47045 Da
Function T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity)
Tissue Specificity Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus
Cellular Localization Nucleus (Potential).
Database Links
Entrez Gene 6911
Nucleotide Accession NP_004599.2
Application

Application

TBX6 Antibody (Center W158) western blot analysis in mouse liver tissue and Hela cell line lysates (35ug/lane).This demonstrates the TBX6 antibody detected the TBX6 protein (arrow).

Application

TBX6 Antibody (Center W158) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:50~100 FC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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