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TDRD7 Antibody (C-term)

Catalog Number:OM222768
OM222768
Discount Price
OM222768-100ul
1~2 Week
100ul
OM222768-50ul
50ul
OM222768-20ul
20ul
1~2 Week
Product Profile
Product Name TDRD7 Antibody (C-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms PCTAIRE2BP
Alternative Names TDRD7
PCTAIRE2BP
Tudor domain-containing protein 7
PCTAIRE2-binding protein
Tudor repeat associator with PCTAIRE 2
Molecular Weight(MW) 123586 Da
Function Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis
Tissue Specificity This TDRD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 807-835 amino acids from the C-terminal region of human TDRD7.
Cellular Localization Cytoplasm. Note=Localizes to cytoplasmic RNA granules. Present in chromatoid body (CB) of spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids (By similarity)
Database Links
Entrez Gene 23424
Nucleotide Accession NP_055105.2
Application

Application

TDRD7 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TDRD7 antibody detected the TDRD7 protein (arrow).

Application

TDRD7 Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the TDRD7 antibody detected the TDRD7 protein (arrow).

Application

TDRD7 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TDRD7 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

TDRD7 Antibody (C-term) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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