DNTT TDT DNA nucleotidylexotransferase Terminal addition enzyme Terminal deoxynucleotidyltransferase
Molecular Weight(MW)
58536 Da
Function
Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells
Tissue Specificity
This TdT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-475 amino acids from the C-terminal region of human TdT.
TdT Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TdT antibody detected the TdT protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.