Application
TFB2M Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TFB2M Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
TFB2M Antibody (C-term) western blot analysis in K562,WiDr cell line lysates (35ug/lane).This demonstrates the TFB2M antibody detected the TFB2M protein (arrow).| Product Name | TFB2M Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:50~100 WB |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NS5ATP5 |
|---|---|
| Alternative Names | TFB2M NS5ATP5 Dimethyladenosine transferase 2 mitochondrial Hepatitis C virus NS5A-transactivated protein 5 Mitochondrial 12S rRNA dimethylase 2 Mitochondrial transcription factor B2 S-adenosylmethionine-6-N' N'-adenosyl(rRNA) dimethyltransferase |
| Molecular Weight(MW) | 45349 Da |
| Function | S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity |
| Tissue Specificity | Ubiquitously expressed. |
| Cellular Localization | Mitochondrion. |
| Entrez Gene | 64216 |
|---|---|
| Nucleotide Accession | NP_071761.1 |
Application
TFB2M Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TFB2M Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
TFB2M Antibody (C-term) western blot analysis in K562,WiDr cell line lysates (35ug/lane).This demonstrates the TFB2M antibody detected the TFB2M protein (arrow).| Application Notes | IHC:1:50~100 WB |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
