TFAP2B Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TFAP2B antibody detected the TFAP2B protein (arrow).
TFAP2B Transcription factor AP-2-beta Activating enhancer-binding protein 2-beta
Molecular Weight(MW)
50474 Da
Function
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia
Tissue Specificity
This TFAP2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 480-510 amino acids from the C-terminal region of human TFAP2B.
TFAP2B Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TFAP2B antibody detected the TFAP2B protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.