Application
TGFBRAP1 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TGFBRAP1 antibody detected the TGFBRAP1 protein (arrow).Application
TGFBRAP1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TGFBRAP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | TGFBRAP1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TGFBRAP1 Transforming growth factor-beta receptor-associated protein 1 |
|---|---|
| Molecular Weight(MW) | 97158 Da |
| Function | Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2 |
| Tissue Specificity | This TGFBRAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-528 amino acids from the C-terminal region of human TGFBRAP1. |
| Cellular Localization | Cytoplasm. Note=Colocalizes with TGF-beta receptors in the absence of signaling |
| Entrez Gene | 9392 |
|---|---|
| Nucleotide Accession | NP_004248.2 NP_001136093.1 |
Application
TGFBRAP1 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TGFBRAP1 antibody detected the TGFBRAP1 protein (arrow).
Application
TGFBRAP1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TGFBRAP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
