Application
THEMIS Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the THEMIS antibody detected the THEMIS protein (arrow).Application
THEMIS Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human thymoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of THEMIS Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | THEMIS Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C6orf190, C6orf207 |
|---|---|
| Alternative Names | THEMIS C6orf190 C6orf207 Protein THEMIS Thymocyte-expressed molecule involved in selection |
| Molecular Weight(MW) | 73452 Da |
| Function | Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk (By similarity) |
| Tissue Specificity | This THEMIS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 566-595 amino acids from the C-terminal region of human THEMIS. |
| Cellular Localization | Cytoplasm (By similarity). Nucleus (By similarity) |
| Entrez Gene | 387357 |
|---|---|
| Nucleotide Accession | NP_001010923.1 NP_001158157.1 |
Application
THEMIS Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the THEMIS antibody detected the THEMIS protein (arrow).
Application
THEMIS Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human thymoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of THEMIS Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
