Application
Western blot analysis of Thrombomodulin Antibody (Center) in MCF7,HL60,K562,293 cell line lysates(35ug/lane). THBD (arrow) was detected using the purified Pab.Application
Thrombomodulin Antibody (Center) (RB18828) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the Thrombomodulin Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | Thrombomodulin Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | THRM |
|---|---|
| Alternative Names | THBD THRM Thrombomodulin Fetomodulin CD_antigen=CD141 Flags: Precursor |
| Molecular Weight(MW) | 60329 Da |
| Function | Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated |
| Tissue Specificity | Endothelial cells are unique in synthesizing thrombomodulin |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 7056 |
|---|
Application
Western blot analysis of Thrombomodulin Antibody (Center) in MCF7,HL60,K562,293 cell line lysates(35ug/lane). THBD (arrow) was detected using the purified Pab.
Application
Thrombomodulin Antibody (Center) (RB18828) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the Thrombomodulin Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.12% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
