Application
TIAM1 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the TIAM1 antibody detected the TIAM1 protein (arrow).| Product Name | TIAM1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 |
|---|---|
| Molecular Weight(MW) | 177508 Da |
| Function | Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP- dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them Activates RAC1, CDC42, and to a lesser extent RHOA |
| Tissue Specificity | Found in virtually all analyzed tumor cell lines including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas |
| Cellular Localization | Cell junction. Note=Presence of KRIT1, CDH5 and RAP1B is required for its localization to the cell junction |
| Entrez Gene | 7074 |
|---|---|
| Nucleotide Accession | NP_003244.2 |
Application
TIAM1 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the TIAM1 antibody detected the TIAM1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
