Application
TICAM2 Antibody (N-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the TICAM2 antibody detected the TICAM2 protein (arrow).| Product Name | TICAM2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TIRAP3, TIRP, TRAM |
|---|---|
| Alternative Names | TICAM2 TIRAP3 TIRP TRAM TIR domain-containing adapter molecule 2 Putative NF-kappa-B-activating protein 502 TRIF-related adapter molecule Toll-like receptor adaptor protein 3 Toll/interleukin-1 receptor domain-containing protein |
| Molecular Weight(MW) | 26916 Da |
| Function | Functions in LPS-TLR4 signaling to regulate the MYD88- independent pathway during the innate immune response to LPS. Also involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1 |
| Tissue Specificity | Expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle, and pancreas |
| Cellular Localization | Cytoplasm. Golgi apparatus. Cell membrane. Note=Localized to the plasma membrane as a result of myristoylation. Phosphorylation on Ser-16 leads to its depletion from the membrane |
| Entrez Gene | 353376 |
|---|---|
| Nucleotide Accession | NP_001157941.1 NP_067681.1 |
Application
TICAM2 Antibody (N-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the TICAM2 antibody detected the TICAM2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
