Application
TIGIT Antibody (C-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the TIGIT antibody detected the TIGIT protein (arrow).Application
TIGIT Antibody (C-term) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the TIGIT antibody detected the TIGIT protein (arrow).Application
TIGIT Antibody (C-term) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | TIGIT Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | VSIG9, VSTM3 |
|---|---|
| Alternative Names | TIGIT VSIG9 VSTM3 T-cell immunoreceptor with Ig and ITIM domains V-set and immunoglobulin domain-containing protein 9 V-set and transmembrane domain-containing protein 3 |
| Molecular Weight(MW) | 26319 Da |
| Function | Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells |
| Tissue Specificity | Expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level) |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Entrez Gene | 201633 |
|---|---|
| Nucleotide Accession | NP_776160.2 |
Application
TIGIT Antibody (C-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the TIGIT antibody detected the TIGIT protein (arrow).
Application
TIGIT Antibody (C-term) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the TIGIT antibody detected the TIGIT protein (arrow).
Application
TIGIT Antibody (C-term) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
