Application
Western blot analysis of TIFA Antibody (N-term) in CEM cell line lysates (35ug/lane). TIFA (arrow) was detected using the purified Pab.| Product Name | TIFA Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | T2BP |
|---|---|
| Alternative Names | TIFA T2BP TRAF-interacting protein with FHA domain-containing protein A Putative MAPK-activating protein PM14 Putative NF-kappa-B-activating protein 20 TRAF2-binding protein |
| Molecular Weight(MW) | 21445 Da |
| Function | Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism |
| Tissue Specificity | This TIFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58~88 amino acids from the N-terminal region of human TIFA. |
| Entrez Gene | 92610 |
|---|
Application
Western blot analysis of TIFA Antibody (N-term) in CEM cell line lysates (35ug/lane). TIFA (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
