Application
TIPRL Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TIPRL antibody detected the TIPRL protein (arrow).| Product Name | TIPRL Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TIPRL TIP41-like protein Putative MAPK-activating protein PM10 Type 2A-interacting protein |
|---|---|
| Molecular Weight(MW) | 31444 Da |
| Function | May be a allosteric regulator of serine/threonine- protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair |
| Tissue Specificity | This TIPRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-218 amino acids from the C-terminal region of human TIPRL. |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 261726 |
|---|---|
| Nucleotide Accession | NP_001026970.1 |
Application
TIPRL Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TIPRL antibody detected the TIPRL protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
