TLE2 Transducin-like enhancer protein 2 Enhancer of split groucho-like protein 2
Molecular Weight(MW)
79841 Da
Function
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity)
Tissue Specificity
In all tissues examined, mostly in heart, brain, and muscle
Western blot analysis of TLE2 Antibody (Center) in 293, K562 cell line lysates (35ug/lane). TLE2 (arrow) was detected using the purified Pab.
Application Notes
WB:1:50~100
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.