Application
TLR7 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TLR7 antibody detected the TLR7 protein (arrow).| Product Name | TLR7 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TLR7 Toll-like receptor 7 |
|---|---|
| Molecular Weight(MW) | 120922 Da |
| Function | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity) |
| Tissue Specificity | Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type I membrane protein (By similarity). Endosome (By similarity) Lysosome (By similarity). Cytoplasmic vesicle, phagosome Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist (By similarity) |
| Entrez Gene | 51284 |
|---|---|
| Nucleotide Accession | NP_057646.1 |
Application
TLR7 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TLR7 antibody detected the TLR7 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
