Application
TMEM49 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TMEM49 antibody detected the TMEM49 protein (arrow).| Product Name | TMEM49 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TDC1, TMEM49 |
|---|---|
| Alternative Names | VMP1 TDC1 TMEM49 Vacuole membrane protein 1 Transmembrane protein 49 |
| Molecular Weight(MW) | 46238 Da |
| Function | Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity). Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions |
| Tissue Specificity | This TMEM49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-406 amino acids from the C-terminal region of human TMEM49. |
| Cellular Localization | Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein (By similarity) Cell membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein (By similarity). Endoplasmic reticulum |
| Entrez Gene | 81671 |
|---|---|
| Nucleotide Accession | NP_112200.2 |
Application
TMEM49 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TMEM49 antibody detected the TMEM49 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
