Application
Western blot analysis of TMEM67 Antibody (C-term) in MCF-7 cell line lysates (35ug/lane). TMEM67 (arrow) was detected using the purified Pab.Application
Western blot analysis of TMEM67 Antibody (C-term) in CHO cell line lysates (35ug/lane). TMEM67 (arrow) was detected using the purified Pab.| Product Name | TMEM67 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MKS3 |
|---|---|
| Alternative Names | TMEM67 MKS3 Meckelin Meckel syndrome type 3 protein Transmembrane protein 67 |
| Molecular Weight(MW) | 111745 Da |
| Function | Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. Essential for endoplasmic reticulum-associated degradation (ERAD) of surfactant protein C (SFTPC) |
| Tissue Specificity | Widely expressed in adult and fetal tissues. Expressed at higher level in spinal cord |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme (By similarity) |
| Entrez Gene | 91147 |
|---|
Application
Western blot analysis of TMEM67 Antibody (C-term) in MCF-7 cell line lysates (35ug/lane). TMEM67 (arrow) was detected using the purified Pab.
Application
Western blot analysis of TMEM67 Antibody (C-term) in CHO cell line lysates (35ug/lane). TMEM67 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
