Application
TNFAIP8 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TNFAIP8 antibody detected the TNFAIP8 protein (arrow).Application
TNFAIP8 Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | TNFAIP8 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNFAIP8; Tumor necrosis factor alpha-induced protein 8; Head and neck tumor and metastasis-related protein; MDC-3.13; NF-kappa-B-inducible DED-containing protein; SCC-S2; TNF-induced protein GG2-1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TNFAIP8 Tumor necrosis factor alpha-induced protein 8 Head and neck tumor and metastasis-related protein MDC-3.13 NF-kappa-B-inducible DED-containing protein SCC-S2 TNF-induced protein GG2-1 |
|---|---|
| Molecular Weight(MW) | 23003 Da |
| Function | Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation |
| Tissue Specificity | Expressed at high levels in the spleen, lymph node, thymus, thyroid, bone marrow and placenta. Expressed at high levels both in various tumor tissues, unstimulated and cytokine- activated cultured cells. Expressed at low levels in the spinal cord, ovary, lung, adrenal glands, heart, brain, testis and skeletal muscle |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 25816 |
|---|---|
| Nucleotide Accession | NP_055165.2 NP_001071122.1 |
Application
TNFAIP8 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TNFAIP8 antibody detected the TNFAIP8 protein (arrow).
Application
TNFAIP8 Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
