Application
Western blot analysis of TNFRSF1B Antibody (C-term) in MDA-MB435 cell line lysates (35ug/lane). TNFRSF1B (arrow) was detected using the purified Pab.| Product Name | TNFRSF1B Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TNFBR, TNFR2 |
|---|---|
| Alternative Names | TNFRSF1B TNFBR TNFR2 Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor receptor 2 Tumor necrosis factor receptor type II p75 p80 TNF-alpha receptor CD_antigen=CD120b INN=Etanercept Tumor necrosis factor receptor superfami |
| Molecular Weight(MW) | 48291 Da |
| Function | Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity |
| Tissue Specificity | This TNFRSF1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 406~435 amino acids from the C-terminal region of human TNFRSF1B. |
| Cellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein Tumor necrosis factor-binding protein 2: Secreted |
| Entrez Gene | 7133 |
|---|
Application
Western blot analysis of TNFRSF1B Antibody (C-term) in MDA-MB435 cell line lysates (35ug/lane). TNFRSF1B (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
