Application
Western blot analysis of TNFRSF25 Antibody (C-term) in CEM cell line lysates (35ug/lane). TNFRSF25 (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with TNFRSF25 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.Application
Confocal immunofluorescent analysis of TNFRSF25 Antibody (C-term)(Cat#AP8997b) with HepG2 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).| Product Name | TNFRSF25 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | APO3, DDR3, DR3, TNFRSF12, WSL, WSL1 |
|---|---|
| Alternative Names | TNFRSF25 APO3 DDR3 DR3 TNFRSF12 WSL WSL1 Tumor necrosis factor receptor superfamily member 25 Apo-3 Apoptosis-inducing receptor AIR Apoptosis-mediating receptor DR3 Apoptosis-mediating receptor TRAMP Death receptor 3 Lymphocyte-associated rece |
| Molecular Weight(MW) | 45385 Da |
| Function | Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis |
| Tissue Specificity | Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate |
| Cellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 9: Cell membrane; Single-pass type I membrane protein Isoform 3: Secreted. Isoform 5: Secreted. Isoform 7: Secreted. Isoform 10: Secreted. |
| Entrez Gene | 8718 |
|---|
Application
Western blot analysis of TNFRSF25 Antibody (C-term) in CEM cell line lysates (35ug/lane). TNFRSF25 (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with TNFRSF25 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application
Confocal immunofluorescent analysis of TNFRSF25 Antibody (C-term)(Cat#AP8997b) with HepG2 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
