Application
TNFSF13B Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TNFSF13B antibody detected the TNFSF13B protein (arrow).Application
TNFSF13B Antibody (N-term) (AP13996a)immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TNFSF13B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | TNFSF13B Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; B-cell-activating factor; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; CD_antigen=CD |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BAFF BLYS TALL1 TNFSF20 ZTNF4 |
|---|---|
| Alternative Names | TNFSF13B BAFF BLYS TALL1 TNFSF20 ZTNF4 Tumor necrosis factor ligand superfamily member 13B B lymphocyte stimulator B-cell-activating factor Dendritic cell-derived TNF-like molecule TNF- and APOL-related leukocyte expressed ligand 1 CD_antigen=CD |
| Molecular Weight(MW) | 31223 Da |
| Function | Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response |
| Tissue Specificity | Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T- cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas. Isoform 2 is expressed in many myeloid cell lines |
| Cellular Localization | Cell membrane; Single-pass type II membrane protein |
| Entrez Gene | 10673 |
|---|---|
| Nucleotide Accession | NP_006564.1 NP_001139117.1 |
Application
TNFSF13B Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TNFSF13B antibody detected the TNFSF13B protein (arrow).
Application
TNFSF13B Antibody (N-term) (AP13996a)immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TNFSF13B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
