Application
Western blot analysis of TNFSF18 (arrow) using rabbit polyclonal TNFSF18 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TNFSF18 gene.| Product Name | TNFSF18 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNFSF18; AITRL; GITRL; TL6; Tumor necrosis factor ligand superfamily member 18; Activation-inducible TNF-related ligand; Glucocorticoid-induced TNF-related ligand |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | AITRL GITRL TL6 |
|---|---|
| Alternative Names | TNFSF18 AITRL GITRL TL6 Tumor necrosis factor ligand superfamily member 18 Activation-inducible TNF-related ligand Glucocorticoid-induced TNF-related ligand |
| Molecular Weight(MW) | 22724 Da |
| Function | Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T- cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B |
| Tissue Specificity | Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells |
| Cellular Localization | Cell membrane; Single-pass type II membrane protein |
| Entrez Gene | 8995 |
|---|---|
| Nucleotide Accession | NP_005083.2 |
Application
Western blot analysis of TNFSF18 (arrow) using rabbit polyclonal TNFSF18 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TNFSF18 gene.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
