The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008]
Alternative Names
GITR ligand GITRLigand glucocorticoid-induced TNF-related ligand glucocorticoid-induced-tumor necrosis factor receptor ligand RP1-15D23.1 TNF alpha family member GITR ligand GITRL TNF superfamily member 18 TNF superfamily member 18 MGL transmembrane type II protein tumor necrosis factor ligand 2a type II membrane protein