Application
TNIP3 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (15ug/lane).This demonstrates the TNIP3 antibody detected the TNIP3 protein (arrow).Application
TNIP3 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TNIP3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | TNIP3 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNIP3; ABIN3; LIND; TNFAIP3-interacting protein 3; A20-binding inhibitor of NF-kappa-B activation 3; Listeria-induced gene protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ABIN3 LIND |
|---|---|
| Alternative Names | TNIP3 ABIN3 LIND TNFAIP3-interacting protein 3 A20-binding inhibitor of NF-kappa-B activation 3 Listeria-induced gene protein |
| Molecular Weight(MW) | 38943 Da |
| Function | Binds to zinc finger protein TNFAIP3 and inhibits NF- kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13- acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding |
| Tissue Specificity | Highly expressed in lung, lymph node, thymus and fetal liver. Expressed at lower levels in bone marrow, brain, kidney, spleen, leukocytes and tonsils. Could be detected in heart, salivary gland, adrenal gland, pancreas, ovary and fetal brain. High levels detected in liver, colon, small intestine, muscle, stomach, testis, placenta, thyroid, uterus, prostate, skin and PBL |
| Entrez Gene | 79931 |
|---|---|
| Nucleotide Accession | NP_001122315.1 NP_079149.3 |
Application
TNIP3 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (15ug/lane).This demonstrates the TNIP3 antibody detected the TNIP3 protein (arrow).
Application
TNIP3 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TNIP3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
