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TOLLIP Antibody (N-term)

Catalog Number:OM223377
OM223377
Discount Price
OM223377-100ul
1~2 Week
100ul
OM223377-50ul
50ul
OM223377-20ul
20ul
1~2 Week
Product Profile
Product Name TOLLIP Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias TOLLIP; Toll-interacting protein
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names TOLLIP
Toll-interacting protein
Molecular Weight(MW) 30282 Da
Function Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity
Tissue Specificity This TOLLIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human TOLLIP.
Cellular Localization Cytoplasm (Probable).
Database Links
Entrez Gene 54472
Application

Application

Western blot analysis of hTollip-M1 in A2058 cell line lysates (35ug/lane).TOLLIP (arrow) was detected using the purified Pab.

Application

Western blot analysis of TOLLIP (arrow) using rabbit polyclonal TOLLIP Antibody .

Application

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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