Application
Western blot analysis on (a) 293T and (b) Jurkat cell lysates using anti-TorC3 RabMAb (Cat. #AJ1782a).Application
Immunohistochemical analysis of paraffin-embedded human tonsils using anti-TorC3 RabMAb (Cat. #AJ1782a).| Product Name | TorC3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR3440 |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1000~10000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TORC3 |
|---|---|
| Molecular Weight(MW) | 66959 Da |
| Function | Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) |
| Tissue Specificity | Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach |
| Cellular Localization | Nucleus. Cytoplasm. Note=Appears to be mainly nuclear |
| Entrez Gene | 64784 |
|---|
Application
Western blot analysis on (a) 293T and (b) Jurkat cell lysates using anti-TorC3 RabMAb (Cat. #AJ1782a).
Application
Immunohistochemical analysis of paraffin-embedded human tonsils using anti-TorC3 RabMAb (Cat. #AJ1782a).| Application Notes | WB:1:1000~10000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
