Application
Western blot analysis of TOX3 Antibody (Center) in mouse stomach tissue lysates (35ug/lane). TOX3 (arrow) was detected using the purified Pab.Application
TOX3 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TOX3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.Application
Western blot analysis of TOX3 Antibody (Center) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in MDA-MB453 cell line lysate. TOX3 Antibody (Center) (arrow) was detected using the purified Pab (1:60/250 dilution).Application
Western blot analysis of TOX3 Antibody (Center) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in mouse lung tissue lysate. TOX3 Antibody (Center) (arrow) was detected using the purified Pab (1:60/250 dilution).Application
TOX3 Antibody (Center) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | TOX3 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TOX3; CAGF9; TNRC9; TOX high mobility group box family member 3; CAG trinucleotide repeat-containing gene F9 protein; Trinucleotide repeat-containing gene 9 protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CAGF9 TNRC9 |
|---|---|
| Alternative Names | TOX3 CAGF9 TNRC9 TOX high mobility group box family member 3 CAG trinucleotide repeat-containing gene F9 protein Trinucleotide repeat-containing gene 9 protein |
| Molecular Weight(MW) | 63342 Da |
| Function | Transcriptional coactivator of the p300/CBP-mediated trancription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region |
| Tissue Specificity | Expressed mainly in epithelial cells. Expressed in the central nervous system (CNS), in the ileum and within the brain in the frontal and occipital lobe |
| Cellular Localization | Nucleus (Probable). |
| Entrez Gene | 27324 |
|---|
Application
Western blot analysis of TOX3 Antibody (Center) in mouse stomach tissue lysates (35ug/lane). TOX3 (arrow) was detected using the purified Pab.
Application
TOX3 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TOX3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
Western blot analysis of TOX3 Antibody (Center) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in MDA-MB453 cell line lysate. TOX3 Antibody (Center) (arrow) was detected using the purified Pab (1:60/250 dilution).
Application
Western blot analysis of TOX3 Antibody (Center) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in mouse lung tissue lysate. TOX3 Antibody (Center) (arrow) was detected using the purified Pab (1:60/250 dilution).
Application
TOX3 Antibody (Center) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
