Application
TPM2 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the TPM2 antibody detected the TPM2 protein (arrow).| Product Name | TPM2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TPM2; TMSB; Tropomyosin beta chain; Beta-tropomyosin; Tropomyosin-2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TMSB |
|---|---|
| Alternative Names | TPM2 TMSB Tropomyosin beta chain Beta-tropomyosin Tropomyosin-2 |
| Molecular Weight(MW) | 32851 Da |
| Function | Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization (By similarity) |
| Tissue Specificity | Present in primary breast cancer tissue, absent from normal breast tissue |
| Cellular Localization | Cytoplasm, cytoskeleton. |
| Entrez Gene | 7169 |
|---|---|
| Nucleotide Accession | NP_998839.1 |
Application
TPM2 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the TPM2 antibody detected the TPM2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
