Application
TPM4 Antibody (N-term) western blot analysis in U251,A549,Jurkat cell line lysates (35ug/lane).This demonstrates the TPM4 antibody detected the TPM4 protein (arrow).Application
TPM4 Antibody (N-term) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | TPM4 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TPM4; Tropomyosin alpha-4 chain; TM30p1; Tropomyosin-4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TPM4 Tropomyosin alpha-4 chain TM30p1 Tropomyosin-4 |
|---|---|
| Molecular Weight(MW) | 28522 Da |
| Function | Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium |
| Tissue Specificity | Detected in cardiac tissue and platelets, the form found in cardiac tissue is a higher molecular weight than the form found in platelets. Expressed at higher levels in the platelets of hypertensive patients with cardiac hypertrophy than in the platelets of hypertensive patients without cardiac hypertrophy (at protein level) |
| Cellular Localization | Cytoplasm, cytoskeleton. |
| Entrez Gene | 7171 |
|---|---|
| Nucleotide Accession | NP_003281.1 |
Application
TPM4 Antibody (N-term) western blot analysis in U251,A549,Jurkat cell line lysates (35ug/lane).This demonstrates the TPM4 antibody detected the TPM4 protein (arrow).
Application
TPM4 Antibody (N-term) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
