Application
TRAF4 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TRAF4 antibody detected the TRAF4 protein (arrow).| Product Name | TRAF4 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRAF4; CART1; MLN62; RNF83; TNF receptor-associated factor 4; Cysteine-rich domain associated with RING and Traf domains protein 1; Metastatic lymph node gene 62 protein; RING finger protein 83 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CART1 MLN62 RNF83 |
|---|---|
| Alternative Names | TRAF4 CART1 MLN62 RNF83 TNF receptor-associated factor 4 Cysteine-rich domain associated with RING and Traf domains protein 1 Metastatic lymph node gene 62 protein RING finger protein 83 |
| Molecular Weight(MW) | 53543 Da |
| Function | Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (By similarity). Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions |
| Tissue Specificity | Expressed in epithelial cells of thymus, dendritic cells of lymph node, and in the basal cell layer of epithelia such as epidermis, nasopharynx, respiratory tract, salivary gland, and esophagus |
| Cellular Localization | Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Cell junction, tight junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton (Probable) |
| Entrez Gene | 9618 |
|---|---|
| Nucleotide Accession | NP_004286.2 |
Application
TRAF4 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TRAF4 antibody detected the TRAF4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
