Application
TREM2 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TREM2 antibody detected the TREM2 protein (arrow).| Product Name | TREM2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TREM2; Triggering receptor expressed on myeloid cells 2; Triggering receptor expressed on monocytes 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TREM2 Triggering receptor expressed on myeloid cells 2 Triggering receptor expressed on monocytes 2 |
|---|---|
| Molecular Weight(MW) | 25447 Da |
| Function | May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells |
| Tissue Specificity | Expressed on macrophages and dendritic cells but not on granulocytes or monocytes. In the CNS strongest expression seen in the basal ganglia, corpus callosum, medulla oblongata and spinal cord |
| Cellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein (Potential) Isoform 3: Secreted (Potential). |
| Entrez Gene | 54209 |
|---|---|
| Nucleotide Accession | NP_061838.1 |
Application
TREM2 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TREM2 antibody detected the TREM2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
