Application
TREM1 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TREM1 antibody detected the TREM1 protein (arrow).| Product Name | TREM1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TREM1; Triggering receptor expressed on myeloid cells 1; Triggering receptor expressed on monocytes 1; CD_antigen=CD354; Flags: Precursor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TREM1 Triggering receptor expressed on myeloid cells 1 Triggering receptor expressed on monocytes 1 CD_antigen=CD354 Flags: Precursor |
|---|---|
| Molecular Weight(MW) | 26387 Da |
| Function | Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock |
| Tissue Specificity | Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in normal cells than malignant cells. Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes Strongly expressed in acute inflammatory lesions caused by bacteria and fungi. Isoform 2 was detected in the lung, liver and mature monocytes |
| Cellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein (Potential) |
| Entrez Gene | 54210 |
|---|---|
| Nucleotide Accession | NP_061113.1 |
Application
TREM1 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TREM1 antibody detected the TREM1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
